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Overview
The Proteonano™ technology uses peptides and small molecules modified on the surface of magnetic nanoparticles (surface-modified, monodisperse magnetic nanoparticles ,S3MNPs) for plasma/serum protein capture. This allows selective capture of low abundant proteins, resulting in relative depletion of high abundant proteins. This improves LC-MS/MS detection depth, promoting the effectiveness of untargeted proteomic analysis.
What's included?
EN-Binding Buffer | Promote the binding of protein and magnetic beads |
EN-Wash Buffer | Clean the non-specific binding proteins |
One-step Digestion Buffer | Protein denaturation、reduction and digestion |
Powder of Trypsin/Lys-C Mix | Powder of Trypsin/Lys-C Mix |
Ending Buffer | Stop digestion |
Activating Buffer | Activate C18 pipette tip |
Wash Buffer | Clean C18 membrane |
Elution Buffer | Elute peptides from C18 membrane |
Resuspend Buffer | Peptide powder reconstitution solution |
Desalting Tips | C18 desalting tips |
Enrichment Nanobeads | Low-abundance protein enrichment magnetic nanobeads |
Supporting Data
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Documents
Protocol
Instructions to Proteonano™ Plasma Proteome Enrich Kit (Operational Manual)
Application Note
Proteonano™Ultraplex Platform for Robust and Fast Large cohort Proteomic Studies
Data sheet
A Scalable and Standardized Workflow for Large-Cohort Proteomics
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